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As a potent inhibitor of phosphodiesterase type 5 (PDE5), tadalafil works by relaxing smooth muscles and increasing blood flow to specific areas of the body. While extensively studied for its efficacy and safety in clinical settings, the natural occurrence of tadalafil in the environment remains an area of scientific interest. This study aims to investigate the presence of tadalafil in nature and its potential ecological impact. Introduction:Tadalafil, marketed under the brand name Cialis, is a widely prescribed pharmaceutical compound used...